Change in Weight Status and Development of Hypertension.
نویسندگان
چکیده
OBJECTIVE To examine the association of BMI percentile and change in BMI percentile to change in blood pressure (BP) percentile and development of hypertension (HTN). METHODS This retrospective cohort included 101 606 subjects age 3 to 17 years from 3 health systems across the United States. Height, weight, and BPs were extracted from electronic health records, and BMI and BP percentiles were computed with the appropriate age, gender, and height charts. Mixed linear regression estimated change in BP percentile, and proportional hazards regression was used to estimate risk of incident HTN associated with BMI percentile and change in BMI percentile. RESULTS The largest increases in BP percentile were observed among children and adolescents who became obese or maintained obesity. Over a median 3.1 years of follow-up, 0.3% of subjects developed HTN. Obese children ages 3 to 11 had twofold increased risk of developing HTN compared with healthy weight children. Obese children and adolescents had a twofold increased risk of developing HTN, and severely obese children had a more than fourfold increased risk. Compared with those who maintained a healthy weight, children and adolescents who became obese or maintained obesity had a more than threefold increased risk of incident HTN. CONCLUSIONS We observed a strong, statistically significant association between increasing BMI percentile and increases in BP percentile, with risk of incident HTN associated primarily with obesity. The adverse impact of weight gain and obesity in this cohort over a short period underscores the early need for effective strategies for prevention of overweight and obesity.
منابع مشابه
Evaluation of Growth Status in Children with Congenital Heart Disease: A Case- Control Study
Background: Children with congenital heart disease (CHD) are prone to malnutrition and growth retardation. This study aimed to compare growth status between children with CHD and healthy children. Materials and Methods: This case–control study included 310 children with CHD and 300 healthy children matched in age and gender. CHD patients grouped according to cardiac diagnosis: ...
متن کاملEffects of Glutamine Supplementation on Growth Performance and Antioxidant Status in Broilers with Pulmonary Hypertension Syndrome (PHS)
The present study examined the antioxidant defense of glutamine on plasma and liver antioxidant status in broilers under PHS with respect to changes in the levels of lipid peroxidation marker malondialdehyde (MDA), total antioxidant status (TAS) and the activities of anti peroxidative enzymes [superoxide dismutase (SOD) and glutathione dependent antioxidant enzymes glutathione peroxidase (GPX)]...
متن کاملThe Prevalence of Hypertension among 7-12 Year Old Schoolchildren in Kerman, Iran: a population-based study
Background:The aim of this study was to find the prevalence of chronic hypertension and prehypertension conditions among children. Methods:In this cross-sectional study, a total of 1017 students in Kerman schools were examined during a period from 2013 to 2014. The weight, height, body mass index (BMI), systolic and diastolic blood pressure and family his...
متن کاملGlucocorticoids-Induced Hypertension: The Prevalence and Risk Factors
Introduction: Despite benefits in the treatment of most autoimmune and inflammatory diseases, glucocorticoids (GCs) have proved side effects including hypertension, diabetes, osteoporosis and lipid disorders. Determining the risk factors for hypertension can facilitate the identification of high-risk individuals and lead to effective control of the side effects. The present study aimed to deter...
متن کاملChanges in wheat production technology and the impact on the rural economy in Fars Province
Introduction The increasing population growth and the need for more agricultural products on the one hand, and on the other hand, the limitations of agricultural development are problems that human beings have always tried to solve. Due to the limited resources and inputs of production, it seems that further production growth is possible through advanced technologies. In fact, technology is so...
متن کاملWho Benefits from Rural Change? A Study on the Nature of Social Status Uplifts in Rural Iran
Changing people social status, particularly upwardly, is often considered an indication of a government success in reaching a fair society, particularly in traditionally rigid structures. This is mainly possible through implementing development plan(s) which is theoretically assumed to result in wiping out traditional rigid structures. In the post-revolutionary Iran, the government took upon it...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Pediatrics
دوره 137 3 شماره
صفحات -
تاریخ انتشار 2016